irritate irritate /ˈɪrɪˌteɪt/

verb

1. () Cause annoyance in; disturb, especially by minor irritations  ( chafe , devil , get at [Informal] , get to , gravel [American] , nark [British, Slang] , nettle , rag , rile , annoy , bother , irritate , vex )
   cause annoyance in; disturb, especially by minor irritations
    Mosquitoes buzzing in my ear really bothers me
   Mosquitoes buzzing in my ear really bothers me
    It irritates me that she never closes the door after she leaves
   It irritates me that she never closes the door after she leaves
   
2. () Excite to an abnormal condition,, chafe or inflame  ( irritate )
   excite to an abnormal condition,, chafe or inflame
    Aspirin irritates my stomach
   Aspirin irritates my stomach
   
3. (physiology) excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus  ( irritate )
   (physiology) excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus
    Irritate the glands of a leaf
   irritate the glands of a leaf